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GLP-1 medications have opened up a new path in weight-loss management. Drugs such as Ozempic and Wegovy are delivering significant results for millions, but the weight loss isn\u2019t targeted. That means if you\u2019re taking a GLP-1, you may notice changes in your face just as quickly as elsewhere on your body. Experts say there are six areas of the face that are most commonly affected. Ahead, two plastic surgeons explain what those areas are\u2014and the treatments and procedures that can help address them.<\/p>\n
GLP-1 medications drive fat loss throughout the body, including in areas where volume plays a role, such as the face. \u201cIt doesn\u2019t discriminate against different types of fat and can affect facial fat, which is necessary for structural support and a youthful look,\u201d says California-based facial plastic surgeon Steven Curti, MD.<\/p>\n
As a result of rapid weight loss, the face can begin to hollow and look deflated. In many cases, the face looks \u201cdownward pulled rather than soft and slim,\u201d says Dr. Curti\u2014an effect many now call \u201cOzempic face.\u201d<\/p>\n
Beyond volume loss, there may be longer-term changes as well. According to Houston plastic surgeon Kristy L. Hamilton, MD, GLP-1 medications can also indirectly affect collagen production, which may make facial hollowness more noticeable over time.<\/p>\n
You may not think your temples have much fat to lose, but they do. Dr. Curti says this area contains a thin fat pad that can become affected with GLP-1\u2013related fat loss. When that tissue becomes depleted, the upper face can collapse inward, creating a concave, hollowed appearance.<\/p>\n
This is often the most noticeable area of change because it\u2019s \u201ccentral to facial balance,\u201d says Dr. Hamilton. Fat loss in the middle of the face can lead to flattening and hollowing of the cheeks, deepening of the nasolabial folds and downward migration of facial tissues.<\/p>\n
Fat loss in the midface can also affect the under-eye area, causing it to appear sunken. \u201cIt occurs when supportive tissue under the eyes is lost, resulting in deepening of the natural orbital hollow,\u201d says Dr. Curti. Dr. Hamilton adds that this can create a tired appearance, thin the skin and accentuate dark circles.<\/p>\n
The jowls are another area commonly affected by GLP-1 weight loss. According to Dr. Curti, fat loss along the jawline can unmask skin laxity that was previously supported by volume. For patients who lose weight quickly or later in life, Dr. Hamilton notes that jowling in this area can be particularly distressing and may contribute to a \u201cturkey neck.\u201d<\/p>\n
\u201cThe neck is especially vulnerable to rapid weight loss because reduced fat support combined with thinner skin can reveal platysmal banding, crepiness and laxity,\u201d says Dr. Hamilton. Often referred to as \u201cOzempic neck,\u201d this occurs when volume disappears quickly and the skin isn\u2019t able to retract.<\/p>\n
With GLP-1 use, the lips can appear thinner. More importantly, Dr. Curti notes that the fat and collagen surrounding the lips may begin to deflate. As a result, lines around the mouth become more visible, making the face appear more aged.<\/p>\n
Fortunately, there are several ways to address these concerns, many with minimal downtime. Injectables are often part of that conversation. \u201cStrategically placed dermal fillers and biostimulators such as Sculptra are ideal for bringing volume back into the middle of the face and can also treat hollowness in the temples,\u201d says Dr. Curti. <\/p>\n
While these treatments can be used under the eyes, Dr. Hamilton advises caution. Instead, she recommends a combination approach that treats each concern individually. \u201cA CO2 laser can improve thin, crepey skin, while microneedling with topical application of a biostimulatory medication is also helpful,\u201d she says.<\/p>\n
The experts agree that the neck and jawline usually require more in-depth procedures, such as a face and necklift. \u201cWhen combined with strategic fat transfer, it\u2019s the gold standard for addressing volume loss, jowling and neck laxity,\u201d says Dr. Hamilton. <\/p>\n
\u201cIt\u2019s possible to restore a taut jawline with skin tightening treatments such as Morpheus8 or Ultherapy, but these modalities can also melt additional fat,\u201d says Dr. Curti. He adds that the neck also needs deep collagen scaffolding and more than just tightening. If you\u2019re not ready for a full necklift, he says Radiesse and PRF or exosome therapy can be useful to firm up slack skin and stimulate tissue regeneration.<\/p>\n<\/p><\/div>\n