{"id":3161,"date":"2026-09-25T08:48:22","date_gmt":"2026-09-25T00:48:22","guid":{"rendered":"https:\/\/nichebeaty.com\/index.php\/2026\/09\/25\/why-a-dna-test-led-me-to-a-double-mastectomy-without-breast-cancer\/"},"modified":"2026-09-25T08:48:22","modified_gmt":"2026-09-25T00:48:22","slug":"why-a-dna-test-led-me-to-a-double-mastectomy-without-breast-cancer","status":"publish","type":"post","link":"https:\/\/nichebeaty.com\/index.php\/2026\/09\/25\/why-a-dna-test-led-me-to-a-double-mastectomy-without-breast-cancer\/","title":{"rendered":"Why a DNA Test Led Me to a Double Mastectomy Without Breast Cancer"},"content":{"rendered":"<p><\/p>\n<div>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\"><em class=\"italic\">Donna Schlessinger, of Paramount+\u2019s \u2018The Real Wolf of Wall Street\u2019 and host of the new podcast<\/em>\u00a0<em class=\"italic\">The Donnasphere, has spent the past few years unraveling a family mystery she never knew existed. Here, she shares how an at-home DNA test, an unexpected discovery and a routine breast MRI ultimately led to one of the biggest decisions of her life.<\/em><\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">It all started with a DNA test. My husband, David, had been telling me since 1990 that there was something about my family background that didn\u2019t add up. I grew up in a Jewish family in Brooklyn. My grandfather was a kosher butcher. As far as I was concerned, there wasn\u2019t much to debate.<\/p>\n<\/div>\n<div>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Then, in 2018, David bought us 23andMe kits. We spit into the tubes, sent them off and waited. When my results came back, I was 99.6 percent Ashkenazi Jewish. I couldn\u2019t have been more pleased. I was right. He was wrong. End of story. Except it wasn\u2019t.<\/p>\n<h2 id=\"a-match-i-couldnt-explain\" class=\"font-canela mb-4 mt-8 text-2xl font-light leading-tight text-black md:text-3xl\">A Match I Couldn\u2019t Explain<\/h2>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">As DNA relatives began popping up, most were distant enough that I didn\u2019t give them much thought. Then one appeared who shared 13.6 percent of my DNA. I had no idea who this person was, but that percentage was enough to make me curious.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">We started comparing notes. We had connections to Brooklyn and Boca Raton, and enough coincidences to keep me interested, but nothing that explained how we could possibly be related. Eventually, the trail went cold. COVID happened. Life happened. I put it aside.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Around the same time, I was continuing something I\u2019d been doing for years: keeping a very close eye on my breast health. I had mammograms, sonograms and regular breast MRIs because I believed breast cancer ran in my family. Getting those MRIs approved was often a production. Insurance would deny them, my doctor would fight for them and somehow we would get them done.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Then, in 2025, an MRI was approved without the usual fight. Ironically, that was the one that found something.<\/p>\n<h2 id=\"the-mri-that-changed-everything\" class=\"font-canela mb-4 mt-8 text-2xl font-light leading-tight text-black md:text-3xl\">The MRI That Changed Everything<\/h2>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">I needed an MRI-guided biopsy, and the result was lobular carcinoma in situ, or LCIS. LCIS is a noncancerous breast condition, but it meant my risk of developing invasive breast cancer in the future was higher.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">I went from my regular screening routine to appointments with a breast surgeon and genetic counselor. Suddenly we were talking about risk, family history and what I wanted to do with information that couldn\u2019t tell me exactly what my future held.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Because there were gaps in what I knew about my family medical history, I decided to undergo genetic testing. I was tested for 21 genes associated with hereditary cancer risk, including BRCA1 and BRCA2. Then came four very long weeks of waiting. Everything came back negative.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">That was wonderful news, but I still had LCIS and a decision to make. I could continue with close surveillance and discuss other risk-reducing options with my doctors, or I could have a prophylactic bilateral mastectomy.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">For me, it eventually came down to one thought: I knew I would never regret doing it, but I could regret not doing it. So I chose the mastectomy.<\/p>\n<h2 id=\"but-heres-the-twist\" class=\"font-canela mb-4 mt-8 text-2xl font-light leading-tight text-black md:text-3xl\">But Here\u2019s the Twist<\/h2>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">There\u2019s an important part of this story I haven\u2019t told you yet.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Back in 2020, two years after that 23andMe test, my father became seriously ill. He was 88 and in the throes of dementia. I flew to Florida to be with him, and during that time he revealed something my parents had kept from me for 53 years. He wasn\u2019t my biological father.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">What I didn\u2019t know until later was that my mother had no idea my father knew I was not his biological child. Aside from voicing suspicions about my paternity during their divorce, he never told her or anyone else that he knew for certain. He had carried that secret my entire life. My mother only found out that he knew when I asked her about it.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Suddenly, that mysterious DNA match wasn\u2019t so mysterious anymore.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">I eventually hired a private investigator and found my biological family, opening an entirely new chapter of my life. But the discovery also meant something important for my health: Half of the medical history I had believed was mine for my entire life wasn\u2019t biologically mine at all.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">That included the breast-cancer history that had helped make me so vigilant about screening.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">I still can\u2019t quite get over that part. I had spent years getting breast MRIs, in part, because I believed my father\u2019s mother had breast cancer. It turned out she wasn\u2019t my biological grandmother. Yet one of those MRIs found the LCIS that changed the course of my life.<\/p>\n<h2 id=\"saying-goodbye-to-my-breasts\" class=\"font-canela mb-4 mt-8 text-2xl font-light leading-tight text-black md:text-3xl\">Saying Goodbye to My Breasts<\/h2>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">There was another strange coincidence. Before my LCIS diagnosis, I already had cosmetic breast surgery scheduled for May 5. After 57 years, I was ready to firm things up and make my breasts a little more manageable.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Then I got my diagnosis, and suddenly the breasts I\u2019d been perfectly willing to change were the ones I desperately wanted to keep.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">I canceled the cosmetic surgery and scheduled my mastectomy for the exact same date. The process wasn\u2019t easy. I ultimately went through four surgeries, but today I\u2019m back to playing golf, traveling and living my life. I\u2019ll never know whether breast cancer would have been in my future, and I\u2019m OK with not knowing.<\/p>\n<h2 id=\"finding-my-donnasphere\" class=\"font-canela mb-4 mt-8 text-2xl font-light leading-tight text-black md:text-3xl\">Finding My Donnasphere<\/h2>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">I started writing about my experiences on Substack, and something unexpected happened. People started reaching out. Women shared their own health scares, DNA discoveries, family secrets and stories they hadn\u2019t necessarily felt comfortable talking about before.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">Those conversations made me realize how many of us are walking around with stories that don\u2019t fit neatly into small talk. Sometimes one piece of information can completely change the way you see your health, your family or even yourself.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">That curiosity and connection eventually grew into The Donnasphere, my new podcast, where I get to keep having those conversations and asking the questions I\u2019ve found myself asking over the past few years: Who am I? Where do I belong? And what happens when the story you\u2019ve always known changes suddenly?<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">My mastectomy was my decision, made with my doctors and based on what I knew about my own health and risk. Someone else might make a completely different choice.<\/p>\n<p class=\"text-md mb-6 leading-relaxed text-gray-500\">But when I look back at how I arrived at mine, I can\u2019t help but laugh at where it all began: My husband ordering a DNA test because he was convinced there was something about my family I didn\u2019t know. After all these years, I have to give him this one.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Donna Schlessinger, of Paramount+\u2019s \u2018The Real Wolf of W [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3162,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[55],"tags":[],"_links":{"self":[{"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/posts\/3161"}],"collection":[{"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/comments?post=3161"}],"version-history":[{"count":0,"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/posts\/3161\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/media\/3162"}],"wp:attachment":[{"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/media?parent=3161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/categories?post=3161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nichebeaty.com\/index.php\/wp-json\/wp\/v2\/tags?post=3161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}